Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and ... technique and EO chemical analysis was performed by gas chromatography coupled to a mass spectrometer. Spreng. mg/g extract), gallicacid(. 2019 Feb 27;8(3):50. doi: 10.3390/plants8030050. Download : Download full-size image Some of them are commonly known as boldo and present taxonomic similarities and several synonymies, with antidyspeptic, analgesic and digestive actions. J Ethnopharmacol. ... Plectranthus amboinicus is a recognized plant with … Major chemical components and content (%) of the essential oil in Plectranthus amboinicus under inoculation or not with Claroideoglomus etunicatum and Rhizophagus clarus under low and high addition (20 or 200 mg dm −3 of soil) of P in the substrate. Plectranthus amboinicus (Lour) Spreng belongs to family Lamiaceae, known as country borage in English. In vivo study of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus (Lour.) Flowers References ↑ Chemical constituents Spreng. HHS Phytochemical constituents isolated from Indian species of the genus Plectranthus reported up to 2009 are compiled. The chemical composition of the volatile oil of P. amboinicus growing in different areas had been subjected to various Karpooravalli is a potential remedy for anxiety and stress. The plant is distributed throughout India and is as folklore medicinal plant used to … Spreng … You searched for: Plectranthus amboinicus Remove constraint Plectranthus amboinicus. Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Chemical Composition of The Essential Oil and Aqueous Extract of Plectranthus amboinicus R. Vera 1, J. M. Mondon 2, J. C. Pieribattesti 1. Chen Y-S, Yu H-M, Shie J-J, Cheng T-JR, Wu C-Y, Fang J-M, Wong C-H. 2014. Spreng. P. amboinicus, also commonly known as Indian borage, and is a fleshy, succulent herb famous for its distinct oregano-like flavor and odor. This site needs JavaScript to work properly. The chemical constituents 1–5 of Plectranthus amboinicus and synthetic analogs 8a–d inhibit the binding of AP-1 to its consensus DNA sequence and suppress the expression of lipopolysaccharide-induced TNF-α. Damanik R, Wahlqvist ML, Wattanapenpaiboon N. 2006. NIH Functional characterization of a new terpene synthase from Plectranthus amboinicus. Tungmunnithum D, Garros L, Drouet S, Renouard S, Lainé E, Hano C. Plants (Basel). Table 3 Constituents and Contents of PO2 Fraction From Leaf Essential Oil of Plectranthus amboinicus. Table 3 Constituents and Contents of PO2 Fraction From Leaf Essential Oil of Plectranthus amboinicus. Other parts of the plant contain an essential oil known as thymol. COVID-19 is an emerging, rapidly evolving situation. Chemical Constituents. Essential oil of Plectranthus amboinicus was studied for its chemical composition and larvicidal potential against the malarial vector mosquito Anopheles stephensi. Phytochemical profiling and biological activity of Plectranthus amboinicus (Lour.) Journal of Essential Oil Bearing Plants: Vol. and Plectranthus amboinicus (Lour.) The chemical constituents of CcitEO (lemon grass) were citral 80.7% (45.4 and 35.3% of geranial and neral, respectively) and myrcene ... VASCONCELOS, S. et al. Year 1995 91 Accesses.  |  Fig 2 Leaf of Plectranthus amboinicus Lour. 2-Alkylidenyl-4-cyclopentene-1,3-diones; Anti-inflammation; Plectranthus amboinicus; Rosmarinic acid; Thymoquinone. This study demonstrates that compounds 1-4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. A … Present study describes the comprehensive pharmacognostic aspects of P.hadiensis and P. amboinicus by means of physical and chemical yield parameters. Senthilkumar A, Venkatesalu V. Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (lour.) We use cookies to help provide and enhance our service and tailor content and ads. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Plant phytochemicals possess antimicrobial activity against a wide range of bacteria, yeast and mold, but vary in quantity and quality depending on the bioactive constituents [3,4,53]. Chang, J. M., (2010), Potential Use of Plectranthus amboinicus in the Treatment of Rheumatoid Arthritis, Evidence-Based Complementary and Alternative Medicine, 7(1), 115–120. and essential oil producing capability [8,9]. In the present work, the chemical characterization, antimicrobial, antiparasitic, and cytotoxic properties of the essential oil from Plectranthus amboinicus (Lour.) The genus Plectranthus in India and its chemistry. NLM In India, the genus Plectranthus is found in all the habitats and altitudes, particularly in the Himalaya, the Southern Ghats, and the Nilgiri region. Spreng / Savina Asiimwe, Anna-Karin Borg- Karlsson, Muhammad Azeem, Kamatenesi Maud Mugisha, Agnes Namutebi and Ndukui James Gakunga / International Journal of Pharmaceutical Science Invention, Volume 3 Issue 2, February 2014, PP.19-27 2020 Dec 7;22(45):7847-7857. doi: 10.1039/D0CE01403F. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. The extract also exhibited antiplatelet aggregation ability, antibacterial activity, and antiproliferative effect against cancer cell lines: Caco-2, HCT-15, and MCF-7. GCMS analysis revealed the presence of 11 chemical compounds constituting 97.6% of the total extract composition. 2019 May 28;10:573. doi: 10.3389/fphar.2019.00573. This study demonstrates that compounds 1–4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. 15, No. Phytochemical screening of the ethanolic extract of the leaves was carried out according to the qualitative phytochemical screening tests to evaluate the presence of its chemical constituents such as alkaloid, flavonoid, saponin, triterpenoid, steroid and phenolic. Another analysis obtained thymol (41.3%), carvacrol (13.25%), 1,8-cineole (5.45%), eugenol (4.40%), caryophyllene (4.20%), terpinolene (3.75%), α-pinene (3.20%), β-pinene (2.50%), methyl eugenol (2.10%), and β-phellandrene(1.90%). We then synthesized 2-alkylidenyl-4-cyclopentene-1,3-diones as the designed biomimetics of thymoquinone, and found that compounds 8a, 8b and 8d were more potent TNF-α inhibitors Nevertheless, it is known that the chemical constituents of EO-Pa differed from those of the collected samples from diverse geographical places, in which more than 70 different constituents have been described. Objective: The present investigation was undertaken to explore the possible mechanisms of Plectranthus amboinicus leaf extract in alloxan-induced diabetic rats. This review is an effort to compile all the information reported on its phytochemical and pharmacological activities. The principle constituents include linalool (50.3 %), nerol acetate (11.6%), geranyl acetate (11.7 %) and carvacrol (14.3%). USA.gov. The main chemical compounds found in the essential oil of Coleus amboinicus are carvacrol (28.65%), thymol (21.66%), α-humulene (9.67%), undecanal (8.29%), γ-terpinene (7.76%), p-cymene (6.46%), caryophyllene oxide (5.85%), α-terpineol (3.28%), and β-selinene (2.01%). D. Publisher Dorling Kindersley, London. Request PDF | On Mar 1, 2014, Yuan-Siao Chen and others published Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity | … Plectranthus amboinicus is a plant that ranges from warm temperate areas with dry, mild winters to tropical areas with dry to wet climates. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin, Flavour and Fragrance Journal, 10.1002/ffj.1608, 21, 3, (472-479), (2006). eCollection 2019. Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus. [10,11] Ten components were characterized representing 94.0% of the total components detected. Study Design: Experiment based study. doi: 10.1371/journal.pone.0235416. Key words: , Plectranthus amboinicus, MCF -7, MDA MB 231, Anticancer, Antioxidant. We then synthesized 2-alkylidenyl-4-cyclopentene-1,3-diones as the designed biomimetics of thymoquinone, and found that compounds 8a, 8b and 8d were more potent TNF-α inhibitors. Upper calyx are lip ovate, This study demonstrates that compounds 1-4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. Bioorg Med Chem. The present review is an attempt to generate interest among the masses regarding its immense potential in preventing and treating the several diseases. (PDF) Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity | Jiun-Jie Shie - Academia.edu This study demonstrates that compounds 1-4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. Phytochemical composition and larvicidal activity of essential oils from herbal plants. 2019 Jul;250(1):59-68. doi: 10.1007/s00425-019-03147-w. Epub 2019 Mar 23. Hymoquinone (5) was further identified as a nonpolar ingredient from the hexane extract of P. amboinicus to suppress the expression of lipopolysaccharide-induced tumor necrosis factor-alpha (TNF-α). is a perennial herb belonging to the family Lamiaceae which occurs naturally throughout the tropics and warm regions of Africa, Asia and Australia. Morphological, anatomical Thin Layer Chromatographic profiles, essential oil content and composition were carried out according to the established protocols. P. amboinicus extract, from crude extract to an essential oil, contains innumerable biological constituents owing to its chemical diversity. Spreng and its main compound carvacrol were studied. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Among them, PAEA-fraction 60 contained a major active bioactive compound, hexadecanoic acid, methyl ester (270.0). The stem of Indian borage (Plectranthus amboinicus) was found to be an antioxidant rich fraction as evaluated by in vitro models such as DPPH free radical scavenging, reducing power assay, superoxide anion radical scavenging, and total antioxidant capacity. 2*Medicinal and Aromatic Plants Research Department, National Research Centre, 33 El Bohouth St., Ayushvedah provides all the informations about parnayavani - Coleus amboinicus Benth., Plectranthus amboinicus (Lour.) Front Pharmacol. is a perennial herb belonging to the family Lamiaceae which occurs naturally throughout the tropics and warm regions of Africa, Asia and Australia. Copyright © 2014 Elsevier Ltd. All rights reserved. Thymoquinone (5) was further identified as a nonpolar ingredient from the hexane extract of P. amboinicus to suppress the expression of lipopolysaccharide-induced tumor necrosis factor-alpha (TNF-α). constituents. Place and Duration of Study: Plants were gathered along the East Coast of … Spreng. 22(5):1766–1772. Spreng. Mexican mint has many colloquial names including Spanish thyme, French thyme, Ajwain Patta, Karpooravalli, country borage, and so on. The study aimed to estimate antifungal property and chemical composition of the three medicinal plants Cymbopogon citratus (lemongrass), Cajanus cajan (pigeon pea) and Plectranthus amboinicus (thick leaf thyme) leaves collected from the coastal areas of Guyana. 2011 Feb;8(2):244-52. doi: 10.1002/cbdv.201000048.  |  Maxia A, Sanna C, Frau MA, Piras A, Karchuli MS, Kasture V. Molecules. Traditional Used: C. amboinicus is considered a carminative, lactagogue, analgesic, antipyretic and antiseptic. Sharma S, Chattopadhyay SK, Singh M, Bawankule DU, Kumar S. Phytochemistry. Wang Z, Flores Q, Guo H, Trevizo R, Zhang X, Wang S. CrystEngComm. 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